杨霄鸿,贾明宏,杨天予,刘慧君.分子印迹技术在农药残留检测中的应用进展[J].食品安全质量检测学报,2017,8(2):462-467
分子印迹技术在农药残留检测中的应用进展
Progress of molecular imprinting technique on the determination of pesticides residues
投稿时间:2016-12-28  修订日期:2017-02-20
DOI:
中文关键词:  分子印迹技术  农药残留  固相萃取
英文关键词:molecular imprinting technique  pesticides residues  solid phase extraction
基金项目:“提高人才培养质量建设项目”——北京市本科生研究训练项目(5045225076/006, 5046516544/006)
作者单位
杨霄鸿 农产品有害微生物及农残检测与控制北京市重点实验室, 北京农学院食品科学与工程学院 
贾明宏 农产品有害微生物及农残检测与控制北京市重点实验室, 北京农学院食品科学与工程学院 
杨天予 北京农学院食品科学与工程学院 
刘慧君 农产品有害微生物及农残检测与控制北京市重点实验室, 北京农学院食品科学与工程学院, 食品质量与安全北京实验室 
AuthorInstitution
YANG Xiao-Hong Beijing Key Laboratory of Detection and Control of Spoilage Organisms and Pesticide Residues in Agricultural Products, Beijing University of Agriculture, Food Science and Engineering College, Beijing University of Agriculture 
JIA Ming-Hong Beijing Key Laboratory of Detection and Control of Spoilage Organisms and Pesticide Residues in Agricultural Products, Beijing University of Agriculture, Food Science and Engineering College, Beijing University of Agriculture 
YANG Tian-Yu Food Science and Engineering College, Beijing University of Agriculture 
LIU Hui-Jun Beijing Key Laboratory of Detection and Control of Spoilage Organisms and Pesticide Residues in Agricultural Products, Beijing University of Agriculture, Food Science and Engineering College, Beijing University of Agriculture, Beijing Laboratory for Food Quality and Safety 
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中文摘要:
      分子印迹技术是一种由模板、功能单体和交联剂制备的高分子功能材料以展示其选择性分子识别行为的技术, 因为其具有专一识别性、预定性和实用性等特点, 广泛应用于农药残留检测中。本文概括了分子印迹技术的基础理论、分子聚合物的制备以及该技术在农药残留检测中的应用, 其中主要包括分子印迹在固相萃取、色谱固定相、固相微萃取、分子印迹膜和传感器等方面的应用, 并对其发展趋势进行了展望。近几年, 分子印迹技术与磁性分子、纳米材料、荧光分子、传感器等应用技术结合, 期待在分子印迹固有特异性识别带来的高灵敏度基础上, 实现快速检测技术的突破, 解决现有农残速测仪所测农药品种受限、假阳性高、定量难等缺点, 真正实现高通量快速痕量检测。
英文摘要:
      Molecular imprinting is a technique with the characteristic of selective molecular recognition, which is a kind of polymer-function material made of template, functional monomers and crosslinking agent. It is widely applied for detection of pesticide residues because of specificity recognition, predetermination and practicability. This paper summarized the basic theories and the preparation of molecular imprinting polymers, and reviewed its application in the determination of pesticides residues, such as solid phase extraction, stationary phase of chromatography, solid phase microextraction, molecular imprinted membrane, sensor and so on. Furthermore, the prospect was put forward. In recent years, with the development of molecular imprinting technology combining with magnetic molecules, nanomaterials, fluorescent molecules, sensors and other application technology, it is expected to achieve a breakthrough of rapid detection technology based on high sensitivity of molecular imprinting technology, to solve the existing shortcomings such as limited varieties of pesticide measure instruments, high false-positive and hard quantitative, and then truly achieve high-throughput rapid trace detection.
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